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Rabbit Anti-Rat Topoisomerase II (TOP2) Polyclonal Antibody

Cat. No.VD5N651

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat topoisomerase II. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat topoisomerase II.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C8N46
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Topoisomerase II
Isotype IgG
Immunogen Recombinant protein of rat topoisomerase II
Purification Protein A/G Purified
Purity ≥ 90%
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat TOP2 is a large nuclear enzymatic protein containing conserved DNA cleavage and ATP-binding domains that maintain stable structural conformation under physiological conditions. It resides predominantly within the nuclear compartment of proliferating somatic cell populations. Its large multi-domain catalytic architecture and cell cycle-dependent expression distinguish it from plasma membrane receptors, soluble secreted signaling molecules and cytoplasmic scaffold adaptors with streamlined single-domain assemblies and static single-compartment subcellular localization profiles.

Target Rat Topoisomerase II
Target Synonym DNA topoisomerase 2-alpha; DNA topoisomerase II, alpha isozyme
Gene ID 360243
UniProt ID P41516

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 24 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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