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Rabbit Anti-Rat Topoisomerase II Binding Protein 1 (TOPBP1) Polyclonal Antibody

Cat. No.VD5N928

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat topoisomerase II binding protein 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat topoisomerase II binding protein 1.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C9N191
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Topoisomerase II Binding Protein 1
Isotype IgG
Immunogen Recombinant protein of rat topoisomerase II binding protein 1
Purification Protein A/G Purified
Purity ≥ 90%
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat TOPBP1 is a nuclear scaffold protein with multiple conserved DNA and protein interaction domains that maintain stable protein conformation under physiological conditions. It exists abundantly in dividing cell populations and assembles large multi-protein complexes at chromatin regions within cell nuclei. Its multi-domain genome-stabilizing architecture and nuclear localization differentiate it from secreted cytokines, membrane transporters and cytoplasmic signaling mediators with simplified single-domain assemblies broadly distributed across non-proliferative somatic cell subgroups.

Target Rat Topoisomerase II Binding Protein 1
Target Synonym TOP2BP1; DNA topoisomerase II-beta-binding protein 1
Gene ID 315969
UniProt ID A0A8I6GFZ6

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 24 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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