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Rabbit Anti-Rat Tafazzin (TAZ) Polyclonal Antibody

Cat. No.VD3N419

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat tafazzin. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat tafazzin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N170
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Tafazzin
Isotype IgG
Immunogen Recombinant protein of rat tafazzin
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Tafazzin (TAZ) is an enzyme involved in the remodeling of cardiolipin, a key phospholipid in the inner mitochondrial membrane. It catalyzes the acyl chain exchange of cardiolipin, ensuring its proper composition and function. TAZ is essential for maintaining mitochondrial integrity and function, which are critical for energy production and cellular metabolism. Defects in TAZ are associated with Barth syndrome, a disorder characterized by cardiomyopathy and skeletal myopathy. This enzyme plays a crucial role in mitochondrial dynamics and overall cellular health.

Target Rat Tafazzin
Target Synonym CMD3A; EFE2; EFE; BTHS; XAP-2
Gene ID 363521
UniProt ID Q4KLG6

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Xu, Yang, et al. "The enzymatic function of tafazzin." Journal of Biological Chemistry 281.51 (2006): 39217-39224. https://doi.org/10.1074/jbc.M606100200
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