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Rabbit Anti-Rat SMAD family member 3 (SMAD3) Polyclonal Antibody

Cat. No.VD2N670

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat Smad family member 3. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of rat Smad family member 3.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N169
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat SMAD family member 3
Isotype IgG
Immunogen Recombinant protein of rat Smad family member 3
Purification Protein A Purified
Concentration 0.96 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Smad Family Member 3 (Smad3) is a key intracellular signaling molecule involved in the TGF-β superfamily signaling pathway. It mediates the effects of TGF-β and related cytokines, playing crucial roles in cell proliferation, differentiation, apoptosis, and tissue homeostasis. Smad3 is activated by receptor-regulated Smads and forms complexes that translocate to the nucleus, regulating gene expression. It is essential for embryonic development and tissue repair, and its dysregulation is implicated in fibrosis and cancer. Smad3 is an important target for studying TGF-β signaling and its impact on disease mechanisms in rat models.

Target Rat SMAD family member 3
Target Synonym JV15-2; MADH3; Mothers Against Decapentaplegic Homolog 3
Gene ID 25631
UniProt ID P84025

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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