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Rabbit Anti-Rat Single Ig IL1 Related Receptor (SIGIRR) Polyclonal Antibody

Cat. No.VD2N973

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat single Ig IL1 related receptor. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of rat single Ig IL1 related receptor.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N472
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Single Ig IL1 Related Receptor
Isotype IgG
Immunogen Recombinant protein of rat single Ig IL1 related receptor
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Single Ig IL-1 Related Receptor (SIGIRR) is a negative regulator of inflammatory signaling pathways. It modulates the activity of Toll-like receptors (TLRs) and IL-1 receptor family members, thereby dampening pro-inflammatory responses. SIGIRR is expressed in epithelial cells and immune cells, where it helps maintain immune homeostasis by preventing excessive inflammation. Its function is crucial for balancing immune responses and protecting tissues from inflammatory damage. As a key regulator of immune signaling, SIGIRR is an important target for studying inflammatory diseases and potential therapeutic interventions.

Target Rat Single Ig IL1 Related Receptor
Target Synonym TIR8; Single Ig IL-1R-related molecule; Toll/interleukin-1 receptor 8; Single immunoglobulin domain-containing IL1R-related protein
Gene ID 309106
UniProt ID Q4V892

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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