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Rabbit Anti-Rat Sclerostin (SOST) Polyclonal Antibody

Cat. No.VD2N722

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat sclerostin. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of rat sclerostin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N221
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Sclerostin
Isotype IgG
Immunogen Recombinant protein of rat sclerostin
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Sclerostin is a secreted glycoprotein involved in bone metabolism. It is produced by osteocytes and plays a crucial role in regulating bone formation by inhibiting the Wnt signaling pathway. Sclerostin binds to the LRP5/6 co-receptors, preventing Wnt ligands from activating the canonical Wnt pathway, which is essential for osteoblast differentiation and bone mineralization. In rats, sclerostin is essential for maintaining bone homeostasis and supporting overall skeletal health.

Target Rat Sclerostin
Target Synonym VBCH; Sclerosteosis
Gene ID 80722
UniProt ID Q99P67

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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