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Rabbit Anti-Rat S100 Calcium Binding Protein A16 (S100A16) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat S100 calcium binding protein A16. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat S100 calcium binding protein A16.
Specifications
Target Information
Rat S100 calcium-binding protein A16 (S100A16) is a 103-residue, 11 kDa member of the S100 family containing two canonical EF-hand motifs: a non-canonical N-terminal loop and a C-terminal calcium-binding loop with sub-millimolar affinity. The protein forms non-covalent dimers stabilized by hydrophobic residues at positions 42 and 86, exposing a basic patch for lipid interaction upon calcium binding. Constitutively expressed in lung, spleen and adipose tissue, S100A16 localizes to cytosol and nucleus, associating with lipid droplets and early endosomes. Antibodies raised against full-length recombinant rat S100A16 detect native, calcium-bound and oxidized forms with negligible cross-reactivity to other S100 proteins, enabling selective immunoblot and immunohistochemical visualization in rat tissue homogenates and sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
