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Rabbit Anti-Rat Renal Tumor Antigen (RAGE) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat renal tumor antigen. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat renal tumor antigen.
Specifications
Target Information
Rat Renal Tumor Antigen (RAGE, also termed CA IX in some species) is a cell-surface glycoprotein selectively expressed in renal proximal tubules under hypoxic conditions. It catalyzes hydration of CO₂ to bicarbonate, regulating intracellular pH and promoting tumor cell survival in acidic microenvironments. Its extracellular domain is released into circulation, providing a measurable indicator of renal hypoxia and neoplastic growth. As a specific marker of renal hypoxic stress, RAGE serves as an important target for studies of kidney tumors, ischemic injury, and pH-dependent tumorigenesis.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.