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Rabbit Anti-Rat Receptor Interacting Serine Threonine Kinase 3 (RIPK3) Polyclonal Antibody

Cat. No.VD3N489

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat receptor interacting serine threonine kinase 3. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat receptor interacting serine threonine kinase 3.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N240
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Receptor Interacting Serine Threonine Kinase 3
Isotype IgG
Immunogen Recombinant protein of rat receptor interacting serine threonine kinase 3
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Receptor-Interacting Serine/Threonine Kinase 3 (RIPK3) is a key regulator of necroptosis, a form of programmed cell death. It is activated in response to various stimuli, including TNF-α and viral infections, and interacts with other proteins to form the necrosome complex. RIPK3 phosphorylates MLKL, leading to the formation of pores in the plasma membrane and subsequent cell death. Its activity is essential for maintaining cellular homeostasis and preventing the spread of pathogens. RIPK3 is an important target for studying cell death mechanisms and related diseases in rat models.

Target Rat Receptor Interacting Serine Threonine Kinase 3
Target Synonym RIP3; RIP-like protein kinase 3; Receptor-interacting protein 3
Gene ID 246240
UniProt ID Q9Z2P5

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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