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Rabbit Anti-Rat Programmed Cell Death Protein 1 Ligand 2 (PDL2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat programmed cell death protein 1 ligand 2. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat programmed cell death protein 1 ligand 2.
Specifications
Target Information
Rat Programmed Cell Death Protein 1 Ligand 2 (PD-L2) is a trans-membrane glycoprotein that binds PD-1 on T cells, delivering an inhibitory signal that restrains activation, cytokine release, and proliferation. It is constitutively expressed on dendritic cells, macrophages, and selected epithelia, and is rapidly up-regulated by inflammatory stimuli. PD-L2 thus modulates immune thresholds, preventing excessive tissue damage while permitting pathogen clearance. Antibodies to rat PD-L2 enable precise detection of inhibitory ligand density and functional analysis of PD-1 checkpoint regulation in rat transplantation, autoimmunity, and injury models.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.