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Rabbit Anti-Rat Phosphofructokinase (PFKP) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat phosphofructokinase, platelet. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat phosphofructokinase, platelet.
Specifications
Target Information
Rat phosphofructokinase, platelet (PFKP) is a cytoplasmic tetrameric glycolytic enzyme of the phosphofructokinase family, a rate-limiting regulator of glycolysis. It features a conserved N-terminal regulatory domain, a central catalytic domain with ATP-binding motifs, and a C-terminal allosteric modulation region critical for structural integrity and enzymatic activity. It localizes to the cytoplasm of rat platelets, erythrocytes and brain cells, with negligible levels in liver and muscle tissues. The protein mediates fructose-6-phosphate phosphorylation and glycolytic flux control, with conserved motifs for substrate binding and allosteric regulation. Rat PFKP shares core functional domains with mammalian orthologs, and has distinct tissue specificity differentiating it from PFKM and PFKL.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.