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Rabbit Anti-Rat Oncoprotein Induced Transcript 3 (OIT3) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat oncoprotein induced transcript 3. It is purified by protein A/G. It can be applied to WB and IHC assays of rat oncoprotein induced transcript 3.
Specifications
Target Information
Rat oncoprotein induced transcript 3 (OIT3) is a transmembrane protein encoded by the Oit3 gene in Rattus norvegicus, mapped to chromosome 1. It belongs to the transmembrane 4 superfamily, featuring multiple conserved hydrophobic transmembrane domains and a short C-terminal cytoplasmic tail with no enzymatic motifs. It localizes primarily to cell membrane and endosomal compartments, with tissue-specific expression in rat spleen, lung, liver and immune cells, with low levels in muscle and neural tissues. The protein mediates membrane protein trafficking and cell-cell interaction, with conserved structural motifs critical for subcellular localization. Rat OIT3 shares core domain architectures with mammalian orthologs, and has distinct expression patterns differentiating it from other transmembrane 4 family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.