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Rabbit Anti-Rat Nucleoporin 50kDa (NUP50) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat nucleoporin 50kDa. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat nucleoporin 50kDa.
Specifications
Target Information
Rat nucleoporin 50kDa (Nup50) is a soluble nucleoporin protein of the nuclear pore complex family. It features a conserved N-terminal Ran-binding domain, a central FG-repeat region and a C-terminal nuclear localization signal critical for structural integrity. It localizes to nuclear pore complexes and nucleoplasm, with tissue-specific expression in rat proliferative tissues including thymus, spleen and embryonic liver, with minimal levels in quiescent adult muscle. The protein mediates nucleocytoplasmic transport and cargo interaction, with conserved motifs for binding specificity. Rat Nup50 shares core functional domains with mammalian orthologs, and has distinct binding affinity differentiating it from Nup62 and Nup98.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.