This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Rat Nitric Oxide Synthase 2 (NOS2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat nitric oxide synthase 2, inducible. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat nitric oxide synthase 2, inducible.
Specifications
Target Information
Rat nitric-oxide synthase 2 (iNOS) is a 130 kDa homodimeric flavo-heme enzyme whose N-terminal oxygenase and C-terminal reductase domains generate nitric oxide from L-arginine, fueling antimicrobial and inflammatory responses. A solvent-exposed 16-aa "KVE" loop (aa 450-465) between the heme and BH4 pockets folds into a β-hairpin unique among rat NOS isoforms, presenting a conformational epitope preserved after fixation. Affinity-purified antibodies targeting this loop trace native iNOS in activated macrophages, microglia, and hepatocytes, delivering crisp cytoplasmic puncta and single-band clarity on immunoblots with no cross-reaction to nNOS or eNOS.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.