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Rabbit Anti-Rat Nestin (NES) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat nestin. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat nestin.
Specifications
Target Information
Rat Nestin is a class VI intermediate filament protein, a core structural component and marker of neural stem/progenitor cells and developing tissues. It features a conserved central α-helical rod domain for filament assembly, N-terminal and C-terminal globular domains, and structural motifs critical for cytoskeletal integrity and cell plasticity. It localizes predominantly to the cytoplasm of rat neural tube, neuroepithelium and developing muscle tissues, with negligible expression in mature differentiated cells. The protein mediates cytoskeletal reorganization and cell migration, with conserved motifs for binding to other intermediate filament proteins. Rat Nestin shares core functional domains with mammalian orthologs, and has distinct tissue specificity differentiating it from vimentin and glial fibrillary acidic protein.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.