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Rabbit Anti-Rat Large Multifunctional Peptidase 7 (LMP7) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat large multifunctional peptidase 7. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat large multifunctional peptidase 7.
Specifications
Target Information
Rat Large Multifunctional Peptidase 7 (LMP7, also named PSMB8 or β5i) is an IFN-γ-inducible catalytic subunit of the immunoproteasome. Expressed chiefly in macrophages and lymphocytes, LMP7 replaces the constitutive β5 subunit to generate peptides with hydrophobic C-termini that fit MHC class I binding motifs. Its activity is therefore essential for efficient MHC-I antigen presentation and consequent CD8⁺ T-cell activation. Antibodies detecting LMP7 enable mapping of immunoproteasome-rich cells in inflammation, infection, or autoimmunity studies .
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.