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Rabbit Anti-Rat Lactate Dehydrogenase C (LDHC) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat lactate dehydrogenase C. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat lactate dehydrogenase C.
Specifications
Target Information
Rat lactate dehydrogenase C (LDHC) is a 329-residue testis-specific isoform of the LDH family, forming homotetrameric 140 kDa complexes that catalyze the interconversion of pyruvate and lactate using NADH/NAD⁺. The subunit exhibits a unique Pro → Gln substitution at position 233 within the catalytic loop, conferring enhanced thermal stability and reduced pH sensitivity. Exclusively expressed in post-meiotic spermatocytes and spermatids, LDHC localizes to the cytoplasmic droplet of developing sperm. Antibodies raised against full-length recombinant rat LDHC detect native and acetylated forms with negligible cross-reactivity to LDHA or LDHB, enabling selective immunoblot and immunohistochemical visualization in rat testicular homogenates and epididymal sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.