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Rabbit Anti-Rat Interleukin 17 Receptor D (IL17RD) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat interleukin 17 receptor D. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat interleukin 17 receptor D.
Specifications
Target Information
Rat interleukin 17 receptor D (IL-17RD) is a transmembrane receptor encoded by the Il17rd gene in Rattus norvegicus, mapped to chromosome 3. It belongs to the IL-17 receptor family, featuring an extracellular domain with conserved fibronectin type-III motifs, a single transmembrane segment and an intracellular SEFIR domain. It localizes to cell membrane, with tissue-specific expression in rat lung, kidney, intestine and immune tissues, with limited levels in heart and skeletal muscle. IL-17RD mediates IL-17 cytokine family signal transduction and intracellular cascade modulation. Rat IL-17RD shares conserved structural and functional motifs with mammalian orthologs, and has distinct ligand-binding characteristics differentiating it from other IL-17 receptor subtypes.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.