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Rabbit Anti-Rat Glutathione Peroxidase 1 (GPX1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat glutathione peroxidase 1. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat glutathione peroxidase 1.
Specifications
Target Information
Rat glutathione peroxidase 1 (GPx1) is a key antioxidant enzyme that detoxifies hydrogen peroxide and lipid peroxides, protecting cells from oxidative damage. It uses glutathione as a cofactor to reduce peroxides to harmless products, thereby maintaining cellular redox homeostasis. GPx1 is expressed in many tissues, with high levels in liver, kidney, and heart. Its function is essential for safeguarding cells against oxidative stress, which is implicated in various diseases. As a central component of the antioxidant defense system, GPx1 is an important target for research into oxidative stress mechanisms and potential therapeutic interventions.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Yang, Jian-Guo, et al. "Purification and quantitation of a rat plasma selenoprotein distinct from glutathione peroxidase using monoclonal antibodies." Journal of Biological Chemistry 262.27 (1987): 13372-13375.