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Rabbit Anti-Rat Glucosidase Alpha Acid (GaA) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat glucosidase alpha acid. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat glucosidase alpha acid.
Specifications
Target Information
Rat glucosidase alpha, acid (GAA) is a lysosomal hydrolase with conserved glycoside hydrolase family 31 structural domains, a core mediator of glycogen catabolism in acidic cellular compartments. It features an N-terminal signal peptide for lysosomal targeting, a catalytic domain with active-site residues critical for substrate hydrolysis, and a C-terminal domain for protein stability. It localizes predominantly to the lysosomes of rat skeletal muscle cells, cardiac myocytes and hepatocytes, with negligible expression in extracellular or cytosolic fractions. The protein mediates glycogen breakdown via α-1,4- and α-1,6-glycosidic bond cleavage, with conserved motifs differentiating it from cytosolic α-glucosidases.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.