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Rabbit Anti-Rat Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Polyclonal Antibody

Cat. No.VD2N915

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat eukaryotic translation initiation factor 4E binding protein 1. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of rat eukaryotic translation initiation factor 4E binding protein 1.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N414
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Eukaryotic Translation Initiation Factor 4E Binding Protein 1
Isotype IgG
Immunogen Recombinant protein of rat eukaryotic translation initiation factor 4E binding protein 1
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (4E-BP1) is a key regulator of protein synthesis, controlling the activity of eIF4E, a critical factor for translation initiation. It binds to eIF4E, inhibiting its function and thereby modulating the translation of specific mRNAs. 4E-BP1 is regulated by the mTOR signaling pathway, which affects its phosphorylation state and activity. This protein plays a crucial role in cellular growth, proliferation, and stress responses by influencing translation initiation. As a central component of the mTOR pathway, 4E-BP1 is an important target for studying cellular metabolism and potential therapeutic interventions in related diseases.

Target Rat Eukaryotic Translation Initiation Factor 4E Binding Protein 1
Target Synonym 4EBP1; BP-1; PHAS-I; Phosphorylated Heat and Acid-Stable Protein Regulated By Insulin 1
Gene ID 116636
UniProt ID P63074

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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