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Rabbit Anti-Rat Dopamine Receptor D2 (DRD2) Polyclonal Antibody

Cat. No.VD3N734

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat dopamine receptor D2. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat dopamine receptor D2.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C2N134
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Dopamine Receptor D2
Isotype IgG
Immunogen Recombinant protein of rat dopamine receptor D2
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat dopamine receptor D2 (D2R) is a 443-aa G-protein-coupled receptor that selectively binds dopamine, targeting Gi/o-mediated inhibition of cAMP synthesis and modulation of Ca²⁺ and K⁺ channels. It is expressed predominantly on striatal, pituitary and limbic membranes, where its seven-transmembrane topology presents a unique, species-restricted epitope ideal for antibody generation; anti-D2R immunoreagents detect native and denatured receptor in brain slices, synaptosomes and transfected cells without cross-reacting with D1, D3, D4 or D5 subtypes, providing a precise read-out of dopaminergic signaling.

Target Rat Dopamine Receptor D2
Target Synonym DR-D2; D2DR; D2R
Gene ID 24318
UniProt ID P61169

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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