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Rabbit Anti-Rat Dihydrolipoyl Dehydrogenase (DLD) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat dihydrolipoyl dehydrogenase. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat dihydrolipoyl dehydrogenase.
Specifications
Target Information
Rat dihydrolipoyl dehydrogenase (DLD, E3) is a 54 kDa FAD-linked homodimer that re-oxidizes lipoamide swinging arms within pyruvate, α-ketoglutarate, and branched-chain keto-acid dehydrogenase complexes. A solvent-exposed 16-aa "KVE" loop (aa 189-204) between the FAD and NAD+ domains folds into a β-hairpin unique among rat flavoproteins, presenting a conformational epitope preserved after aldehyde fixation. Affinity-purified antibodies targeting this loop trace native DLD in mitochondrial matrices of liver, heart, and hippocampal neurons, delivering crisp reticular staining and single-band clarity on immunoblots with no cross-reaction to other flavoenzymes.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.