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Rabbit Anti-Rat Cyclin D1 (CCND1) Polyclonal Antibody

Cat. No.VD2N29

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat cyclin D1. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat cyclin D1.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone A13N7
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Cyclin D1
Isotype IgG
Immunogen Recombinant protein of rat cyclin D1
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Rat cyclin D1 is a critical protein in cell cycle regulation, facilitating the transition from G1 to S phase. It forms active complexes with cyclin-dependent kinases (CDK4 and CDK6), phosphorylating retinoblastoma protein and promoting cell cycle progression. Cyclin D1 is expressed in various tissues and is essential for normal cell proliferation and tissue development. Its expression levels are tightly controlled to maintain proper cell cycle dynamics. Dysregulation of cyclin D1 is implicated in numerous cancers due to its role in driving cell division.

Target Rat Cyclin D1
Target Synonym CCN-D1; BCL1; PRAD1; U21B31; G1/S-Specific Cyclin-D1; Parathyroid Adenomatosis 1; B-Cell CLL/Lymphoma 1; G1/S-Specific Cyclin D1; PRAD1 oncogene
Gene ID 58919
UniProt ID P39948

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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