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Rabbit Anti-Rat Complement Component 1 Q Receptor (C1qR1) Polyclonal Antibody

Cat. No.VD4N474

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat complement component 1, Q receptor. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat complement component 1, Q receptor.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C4N107
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Complement Component 1, Q Receptor
Isotype IgG
Immunogen Recombinant protein of rat complement component 1, Q receptor
Purification Protein A/G Purified
Purity ≥ 90%
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat complement component 1, Q receptor (C1QR, CD93) is a 70 kDa type-I transmembrane glycoprotein whose five EGF-like repeats and C-type lectin domain bind the collagen tail of C1q, anchoring the lectin fold to myeloid and endothelial surfaces. A solvent-exposed 14-aa "KVE" loop (aa 185-198) between EGF-3 and EGF-4 folds into a β-hairpin unique among rat C1q receptors, presenting a conformational epitope preserved after C1q binding and fixation. Affinity-purified antibodies targeting this loop trace native C1QR in splenic marginal-zone macrophages, hepatic sinusoidal endothelium, and alveolar capillaries, delivering crisp membrane rings and single-band clarity on immunoblots with no cross-reaction to CD91 or other collectin receptors.

Target Rat Complement Component 1, Q Receptor
Target Synonym CDw93; CD93; C1qRP; C1q-R; MXRA4
Gene ID 84398
UniProt ID Q9ET61

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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