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Rabbit Anti-Rat Complement Component 1 Q Receptor (C1qR1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat complement component 1, Q receptor. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat complement component 1, Q receptor.
Specifications
Target Information
Rat complement component 1, Q receptor (C1QR, CD93) is a 70 kDa type-I transmembrane glycoprotein whose five EGF-like repeats and C-type lectin domain bind the collagen tail of C1q, anchoring the lectin fold to myeloid and endothelial surfaces. A solvent-exposed 14-aa "KVE" loop (aa 185-198) between EGF-3 and EGF-4 folds into a β-hairpin unique among rat C1q receptors, presenting a conformational epitope preserved after C1q binding and fixation. Affinity-purified antibodies targeting this loop trace native C1QR in splenic marginal-zone macrophages, hepatic sinusoidal endothelium, and alveolar capillaries, delivering crisp membrane rings and single-band clarity on immunoblots with no cross-reaction to CD91 or other collectin receptors.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
