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Rabbit Anti-Rat Chymase 1, Mast Cell (CMA1) Polyclonal Antibody

Cat. No.VD2N822

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat chymase 1, mast cell. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of rat chymase 1, mast cell.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N321
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Chymase 1, Mast Cell
Isotype IgG
Immunogen Recombinant protein of rat chymase 1, mast cell
Purification Protein A Purified
Concentration 0.91 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Chymase 1 (CMA1) is a serine protease predominantly expressed in mast cells. It plays a crucial role in the production of angiotensin II from angiotensin I, contributing to blood pressure regulation and inflammation. CMA1 is involved in the degradation of extracellular matrix proteins and the release of bioactive peptides, which modulate immune responses and tissue remodeling. Its activity is essential for maintaining cardiovascular homeostasis and is implicated in allergic reactions and fibrosis. CMA1 is an important target for studying mast cell biology and related inflammatory processes in rat models.

Target Rat Chymase 1, Mast Cell
Target Synonym CYH; CYM; Alpha-chymase; Mast cell protease I
Gene ID 25627
UniProt ID P50339

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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