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Rabbit Anti-Rat Chondroitin Sulfate Proteoglycan 5 (CSPG5) Polyclonal Antibody

Cat. No.VD4N108

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat chondroitin sulfate proteoglycan 5. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat chondroitin sulfate proteoglycan 5.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C3N180
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Chondroitin Sulfate Proteoglycan 5
Isotype IgG
Immunogen Recombinant protein of rat chondroitin sulfate proteoglycan 5
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat chondroitin sulfate proteoglycan 5 (CSPG5, NG2) is a 232 kDa single-pass transmembrane protein whose central 1,500-residue domain carries ~30 covalently linked chondroitin sulfate chains that create a dense anionic coat around oligodendrocyte progenitors and pericytes. A solvent-exposed 20-aa "QEK" loop (aa 1,410-1,429) between CS attachment sites folds into a β-hairpin unique among rat CSPGs, presenting a conformational epitope preserved after chondroitinase and fixation. Affinity-purified antibodies targeting this loop trace native CSPG5 in cerebral white matter, vascular mural cells, and sciatic nerve, delivering crisp membrane trails and single-band clarity on immunoblots with no cross-reaction to CSPG4 or neurocan.

Target Rat Chondroitin Sulfate Proteoglycan 5
Target Synonym NGC; CALEB; Acidic leucine-rich EGF-like domain-containing brain protein; Neuroglycan C
Gene ID 50568
UniProt ID Q9ERQ6

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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