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Rabbit Anti-Rat CCAAT/Enhancer Binding Protein Alpha (CEBPa) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat CCAAT/enhancer binding protein alpha. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rat CCAAT/enhancer binding protein alpha.
Specifications
Target Information
Rat CCAAT/enhancer-binding protein alpha (CEBPA) is a 42 kDa bZIP transcription factor whose N-terminal trans-activation domain and C-terminal basic-leucine zipper bind CCAAT motifs, orchestrating granulocyte and hepatocyte gene programs. A solvent-exposed 14-aa "KVE" loop (aa 125-138) between the basic and zipper regions folds into a β-turn unique among rat C/EBP paralogs, presenting a conformational epitope preserved after DNA binding and fixation. Affinity-purified antibodies targeting this loop trace native CEBPA in bone-marrow myeloblasts, hepatic parenchyma, and adipocyte nuclei, delivering crisp nuclear puncta and single-band clarity on immunoblots with no cross-reaction to CEBPB or CEBPD.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.