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Rabbit Anti-Rat Caspase 1 (CASP1) Polyclonal Antibody

Cat. No.VD2N577

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat caspase 1. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of rat caspase 1.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N76
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Caspase 1
Isotype IgG
Immunogen Recombinant protein of rat caspase 1
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Caspase 1 is a crucial enzyme involved in the inflammatory response and apoptosis. It is a cysteine protease that plays a central role in the activation of inflammatory cytokines such as IL-1β and IL-18 through the inflammasome complex. Caspase 1 is expressed in immune cells like macrophages and dendritic cells, where it mediates pyroptosis, a form of programmed cell death. Its activity is tightly regulated and is essential for maintaining immune homeostasis. Caspase 1 is an important target for understanding inflammatory signaling pathways and immune responses in rat models.

Target Rat Caspase 1
Target Synonym ICE; IL1BC; IL1-BC; P45; Interleukin 1 Beta Converting Enzyme; Apoptosis-Related Cysteine Peptidase; Interleukin-1 beta convertase
Gene ID 25166
UniProt ID P43527

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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