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Rabbit Anti-Rat Ataxin 2 Binding Protein 1 (A2BP1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat ataxin 2 binding protein 1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat ataxin 2 binding protein 1.
Specifications
Target Information
Rat ataxin-2-binding protein 1 (A2BP1, Rbfox1) is a 43 kDa RNA-recognition motif (RRM) protein whose central β-sheet clamps UGCAUG elements, steering neuronal splicing and mRNA stability. A solvent-exposed 17-aa "KVE" loop (aa 135-151) between RNP2 and β3 folds into a β-hairpin unique among rat RRM family members, presenting a conformational epitope preserved after paraformaldehyde fixation. Affinity-purified antibodies targeting this loop trace native A2BP1 in hippocampal perikarya, cerebellar Purkinje cells, and skeletal-muscle nuclei, delivering crisp nuclear speckles and single-band clarity on immunoblots with no cross-reaction to Rbfox2 or Rbfox3.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.