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Rabbit Anti-Rat Apolipoprotein A1 (APOA1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat apolipoprotein A1. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat apolipoprotein A1.
Specifications
Target Information
Rat Apolipoprotein A1 (APOA1) is the major protein component of high-density lipoprotein (HDL) particles. It plays a crucial role in reverse cholesterol transport (RCT), facilitating the removal of excess cholesterol from peripheral tissues to the liver for excretion. APOA1 is primarily synthesized by hepatocytes and released into the bloodstream. It interacts with ATP-binding cassette transporter A1 (ABCA1) to promote cholesterol efflux and with lecithin-cholesterol acyltransferase (LCAT) to mature HDL particles. Additionally, APOA1 has anti-inflammatory properties, reducing the risk of atherosclerosis and cardiovascular diseases.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Ito, Jin-ichi, et al. "Apolipoprotein AI induces translocation of cholesterol, phospholipid, and caveolin-1 to cytosol in rat astrocytes." Journal of Biological Chemistry 277.10 (2002): 7929-7935.