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Rabbit Anti-Rat Amyloid Beta Precursor Protein Binding Protein B3 (APBB3) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat amyloid beta precursor protein binding protein B3. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat amyloid beta precursor protein binding protein B3.
Specifications
Target Information
Rat amyloid beta precursor protein binding protein B3 (APP-BP3) is a 52-kDa cytoplasmic protein predominantly expressed in rat brain (hippocampus, cortex), liver, and kidney. It interacts with amyloid beta precursor protein (APP), regulating APP trafficking, processing, and amyloid-beta (Aβ) peptide generation. Critical for maintaining rat neuronal homeostasis and APP metabolism, it modulates pathways involved in synaptic function and protein degradation. Dysregulated expression associates with Alzheimer's disease-related pathology, neuronal dysfunction, and Aβ aggregation in rat models. As a key mediator of APP processing and Aβ homeostasis, rat APP-BP3 is a critical target for studying neurodegenerative pathobiology and developing therapeutics for Alzheimer's disease.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.