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Rabbit Anti-Rat Alpha-1-Antitrypsin (A1AT) Polyclonal Antibody

Cat. No.VD1N12

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat alpha-1-antitrypsin. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat alpha-1-antitrypsin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone A1N12
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Alpha-1-Antitrypsin
Isotype IgG
Immunogen Recombinant protein of rat alpha-1-antitrypsin
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Rat Alpha-1-Antitrypsin (A1AT) is a serine protease inhibitor primarily produced by the liver and secreted into the bloodstream. It plays a crucial role in protecting tissues from protease-induced damage by inhibiting elastase, plasmin, and thrombin. A1AT also has anti-inflammatory and immunomodulatory properties, making it a potential target for treating inflammatory and immune-mediated diseases.

Target Rat Alpha-1-Antitrypsin
Target Synonym SERPINA1; SPAAT; A1-AT; PI; Serpin Peptidase Inhibitor Clade A(Alpha-1 Antiproteinase/AntiTrypsin)Member 1; Alpha-1 protease inhibitor; Short peptide from AAT; Serpin A1
Gene ID 24648
UniProt ID P17475

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Roll, David E., and Robert H. Glew. "Isolation and characterization of rat alpha-1-antitrypsin." Journal of Biological Chemistry 256.15 (1981): 8190-8196.
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