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Rabbit Anti-Rabbit Matrix Metalloproteinase 9 (MMP9) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rabbit matrix metalloproteinase 9. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rabbit matrix metalloproteinase 9.
Specifications
Target Information
Rabbit matrix metalloproteinase 9 (MMP9) is a secreted zinc-dependent endopeptidase of the MMP family, a core regulator of extracellular matrix (ECM) remodeling and tissue homeostasis. It features a conserved N-terminal signal peptide, a pro-peptide domain, a catalytic domain with zinc-binding motif, and a C-terminal hemopexin-like domain critical for substrate specificity and protein stability. It localizes to the extracellular spaces of rabbit inflammatory, epithelial and stromal cells, with negligible levels in quiescent tissues. The protein mediates ECM degradation and cell migration, with conserved motifs for binding to collagens, gelatin and tissue inhibitors of metalloproteinases (TIMPs). Rabbit MMP9 shares core functional domains with mammalian orthologs, and has distinct substrate selectivity differentiating it from MMP2 and MMP7.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.