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Rabbit Anti-Porcine Cytochrome P450 11A1 (CYP11A1) Polyclonal Antibody

Cat. No.VD4N680

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for porcine cytochrome P450 11A1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of porcine cytochrome P450 11A1.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C4N313
Host Rabbit
Target Species Porcine
Species Reactivity Porcine
Specificity Porcine Cytochrome P450 11A1
Isotype IgG
Immunogen Recombinant protein of porcine cytochrome P450 11A1
Purification Protein A/G Purified
Purity ≥ 90%
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Porcine cytochrome P450 11A1 (CYP11A1) is a mitochondrial membrane-bound monooxygenase, a core component of the steroid hormone biosynthesis pathway. It features a conserved heme-binding domain critical for catalytic activity, an N-terminal mitochondrial targeting sequence, and a hydrophobic membrane anchor region for subcellular localization. It localizes predominantly to the inner mitochondrial membrane of porcine adrenal cortical cells and gonadal tissues, with negligible expression in non-steroidogenic organs. The protein mediates cholesterol side-chain cleavage reactions, with conserved structural motifs differentiating it from other cytochrome P450 family members.

Target Porcine Cytochrome P450 11A1
Target Synonym CYP11A; P450SCC; Cholesterol desmolase; Cholesterol Side Chain Cleavage Enzyme; Cytochrome P450 Family 11 Subfamily A Polypeptide 1
Gene ID 403329
UniProt ID P10612

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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