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Rabbit Anti-Nicotinamide Adenine Dinucleotide (NAD) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for nicotinamide adenine dinucleotide. It is purified by protein A/G. It can be applied to ELISA, CLIA/IHC-Fr and ICC assays of nicotinamide adenine dinucleotide.
Specifications
Target Information
Nicotinamide adenine dinucleotide (NAD) is a redox-active coenzyme composed of adenosine monophosphate and nicotinamide mononucleotide linked through a pyrophosphate bridge. The oxidized form, NAD+, accepts a hydride equivalent at the nicotinamide C4 position to generate NADH, creating a reversible redox pair operating at -320 mV. NAD+ also serves as a substrate for ADP-ribosyltransferases and sirtuins, transferring ADP-ribose or acetyl groups to target proteins. Antibodies raised against NAD-protein conjugates recognize the intact dinucleotide with minimal cross-reactivity to NADP, NADH or related nucleotides, allowing direct detection of NAD distribution in fixed cells and tissue homogenates.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.