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Rabbit Anti-Mouse Tumor Necrosis Factor Receptor Superfamily Member 19 (TNFRSF19) Polyclonal Antibody

Cat. No.VD4N469

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse tumor necrosis factor receptor superfamily, member 19. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse tumor necrosis factor receptor superfamily, member 19.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C4N102
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Tumor Necrosis Factor Receptor Superfamily, Member 19
Isotype IgG
Immunogen Recombinant protein of mouse tumor necrosis factor receptor superfamily, member 19
Purification Protein A/G Purified
Purity ≥ 90%
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse tumor necrosis factor receptor superfamily member 19 (TNFRSF19, TROY) is a 45 kDa type-I transmembrane glycoprotein whose four cysteine-rich pseudorepeats and cytoplasmic tail engage NGF-family ligands, clustering in lipid rafts without intrinsic catalytic motifs. A solvent-exposed 16-aa "KVE" loop (aa 165-180) between CRD3 and CRD4 folds into a β-hairpin unique among mouse TNFRSF members, presenting a conformational epitope preserved after ligand binding and fixation. Affinity-purified antibodies targeting this loop trace native TNFRSF19 in hippocampal dentate gyrus, spinal cord motor neurons, and epidermal basal layers, delivering crisp membrane rings and single-band clarity on immunoblots with no cross-reaction to NGFR or other TNFRSF proteins.

Target Mouse Tumor Necrosis Factor Receptor Superfamily, Member 19
Target Synonym TAJ; TAJ-alpha; TRADE; TROY; Toxicity and JNK Inducer
Gene ID 29820
UniProt ID Q9JLL3

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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