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Rabbit Anti-Mouse TTK Protein Kinase (TTK) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse TTK protein kinase. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse TTK protein kinase.
Specifications
Target Information
Mouse TTK protein kinase is a dual-specificity kinase encoded by the Ttk gene in Mus musculus, mapped to chromosome 15. It belongs to the serine/threonine and tyrosine kinase family, featuring a conserved N-terminal kinase domain with dual phosphorylation activity and a C-terminal regulatory region critical for activation. It localizes to nucleus and cytoplasm, with cell cycle-dependent expression in mouse proliferating cells and enrichment in embryonic tissues, thymus and spleen. The protein mediates cell cycle progression and checkpoint regulation, with conserved motifs for substrate phosphorylation and dimerization. Mouse TTK shares core functional domains with mammalian orthologs, and has distinct substrate specificity differentiating it from other dual-specificity kinase family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.