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Rabbit Anti-Mouse Suppressors of Cytokine Signaling 3 (SOCS3) Polyclonal Antibody

Cat. No.VD2N894

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse suppressors of cytokine signaling 3. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse suppressors of cytokine signaling 3.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N393
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Suppressors of Cytokine Signaling 3
Isotype IgG
Immunogen Recombinant protein of mouse suppressors of cytokine signaling 3
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Suppressor of Cytokine Signaling 3 (SOCS3) is a critical regulator of cytokine signaling pathways. It functions as a negative feedback inhibitor, preventing excessive cytokine responses by binding to and inhibiting the activity of Janus kinases (JAKs) and signal transducer and activator of transcription (STAT) proteins. SOCS3 plays a crucial role in modulating immune responses, inflammation, and metabolic processes. Its expression is induced by various cytokines, ensuring proper signal attenuation and maintaining cellular homeostasis. As a key modulator of cytokine signaling, SOCS3 is an important target for studying immune regulation and potential therapeutic interventions in inflammatory and metabolic diseases.

Target Mouse Suppressors of Cytokine Signaling 3
Target Synonym ATOD4; CIS3; Cish3; MGC71791; SOCS-3; SSI-3; SSI3; Cytokine-inducible SH2 protein 3; STAT-induced STAT inhibitor 3
Gene ID 12702
UniProt ID O35718

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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