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Rabbit Anti-Mouse Succinate Dehydrogenase Complex Subunit C (SDHC) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse succinate dehydrogenase complex subunit C. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse succinate dehydrogenase complex subunit C.
Specifications
Target Information
Mouse Succinate Dehydrogenase Complex Subunit C (SDHC) is an integral membrane protein that anchors Complex II within the inner mitochondrial membrane. It binds ubiquinone, enabling electron transfer from succinate to the respiratory chain while participating in the citric-acid cycle. SDHC is expressed in all aerobic tissues, coupling oxidative metabolism to ATP production. Mutations disrupt Complex II assembly, elevating succinate and promoting pseudohypoxic signaling. As an essential component of mitochondrial energy conversion, SDHC is a key target for studies of oxidative phosphorylation, cancer metabolism, and inherited mitochondrial disorders.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.