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Rabbit Anti-Mouse Secreted Frizzled Related Protein 1 (SFRP1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse secreted frizzled related protein 1. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse secreted frizzled related protein 1.
Specifications
Target Information
Mouse Secreted Frizzled-Related Protein 1 (sFRP1) is a member of the sFRP family that modulates Wnt signaling pathways. It acts as a soluble antagonist by binding to Wnt ligands and preventing their interaction with Frizzled receptors, thereby inhibiting canonical Wnt/β-catenin signaling. sFRP1 is expressed in various tissues and plays a role in embryonic development, cell proliferation, and tissue homeostasis. Its activity is essential for proper neural tube formation and limb development. sFRP1 is an important target for studying Wnt signaling and related developmental processes in mouse models.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Matsuyama, Makoto, et al. "Secreted Frizzled-related protein 1 (Sfrp1) regulates the progression of renal fibrosis in a mouse model of obstructive nephropathy." Journal of Biological Chemistry 289.45 (2014): 31526-31533.
