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Rabbit Anti-Mouse S Antigen (SAG) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse S antigen. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse S antigen.
Specifications
Target Information
Mouse S-antigen (SAG, arrestin-1) is a 48 kDa soluble protein whose N-terminal immunoglobulin-like domain and C-tail clasp light-activated phosphorhodopsin, locking photoreceptors in an inactive state. A solvent-exposed 14-aa "KVE" loop (aa 203-216) between β-strands 7 and 8 folds into a β-hairpin unique among mouse arrestins, presenting a conformational epitope preserved after rhodopsin binding and fixation. Affinity-purified antibodies targeting this loop trace native SAG in outer-segment layer, pineal gland, and limited forebrain neurons, delivering crisp subretinal puncta and single-band clarity on immunoblots with no cross-reaction to β-arrestin-1 or β-arrestin-2.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.