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Rabbit Anti-Mouse R-Spondin 1 (RSPO1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse R-spondin 1. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse R-spondin 1.
Specifications
Target Information
Mouse R-spondin 1 (RSPO1) is a secreted protein that plays a crucial role in regulating Wnt signaling. It enhances Wnt/β-catenin pathway activity by inhibiting the destruction complex, leading to increased β-catenin levels and activation of downstream target genes. RSPO1 is involved in various developmental processes, including embryogenesis, tissue homeostasis, and stem cell maintenance. This protein is also implicated in the regulation of cell proliferation and differentiation, making it an important factor in tissue regeneration and repair.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Levin, Gabriel, et al. "R-Spondin 1 (RSPO1) increases mouse intestinal organoid unit size and survival in vitro and improves tissue-engineered small intestine formation in vivo." Frontiers in bioengineering and biotechnology 8 (2020): 476.