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Rabbit Anti-Mouse Pyruvate Dehydrogenase Kinase 4 (PDK4) Polyclonal Antibody

Cat. No.VD3N527

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse pyruvate dehydrogenase kinase 4. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse pyruvate dehydrogenase kinase 4.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N278
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Pyruvate Dehydrogenase Kinase 4
Isotype IgG
Immunogen Recombinant protein of mouse pyruvate dehydrogenase kinase 4
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Pyruvate Dehydrogenase Kinase 4 (PDK4) is a key enzyme that regulates cellular metabolism by phosphorylating and inactivating the pyruvate dehydrogenase complex. This action redirects pyruvate away from the citric acid cycle, favoring fatty acid oxidation. PDK4 is highly expressed in tissues with high metabolic demands, such as the heart and skeletal muscle. Its activity is crucial for maintaining energy homeostasis during periods of fasting or high energy expenditure. PDK4 is an important target for studying metabolic regulation and potential therapeutic interventions in metabolic disorders.

Target Mouse Pyruvate Dehydrogenase Kinase 4
Target Synonym [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial; Pyruvate Dehydrogenase Kinase Isozyme 4
Gene ID 27273
UniProt ID O70571

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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