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Rabbit Anti-Mouse Pyridoxamine-5'-Phosphate Oxidase (PNPO) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse pyridoxamine-5'-phosphate oxidase. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse pyridoxamine-5'-phosphate oxidase.
Specifications
Target Information
Mouse pyridoxamine-5'-phosphate oxidase (PNPO) is a flavin mononucleotide-dependent cytosolic enzyme, a core mediator of vitamin B6 metabolism. It features a conserved flavin-binding domain critical for catalytic activity, a central substrate-recognition motif for pyridoxamine-5'-phosphate binding, and a C-terminal structural domain for dimerization. It localizes predominantly to the cytoplasm of mouse hepatocytes, renal tubular cells and neuronal tissues, with negligible expression in mature erythrocytes. The protein mediates the oxidation of pyridoxamine-5'-phosphate to pyridoxal-5'-phosphate, with conserved structural elements differentiating it from other flavin-dependent oxidases.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.