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Rabbit Anti-Mouse PTEN Induced Putative Kinase 1 (PINK1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse PTEN induced putative kinase 1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse PTEN induced putative kinase 1.
Specifications
Target Information
Mouse PTEN-Induced Putative Kinase 1 (PINK1) is a serine/threonine kinase involved in maintaining mitochondrial function and integrity. It is localized to the outer mitochondrial membrane and plays a crucial role in the regulation of mitochondrial quality control. PINK1 is essential for the recruitment of Parkin, an E3 ubiquitin ligase, to damaged mitochondria, initiating mitophagy and preventing mitochondrial dysfunction. Its activity is critical for cellular health and is implicated in neurodegenerative diseases such as Parkinson's disease. PINK1 is an important target for studying mitochondrial biology and related disorders in mouse models.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.