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Rabbit Anti-Mouse Protein Tyrosine Phosphatase Receptor Type H (PTPRH) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse protein tyrosine phosphatase receptor type H. It is purified by protein A/G. It can be applied to WB and IHC assays of mouse protein tyrosine phosphatase receptor type H.
Specifications
Target Information
Mouse protein-tyrosine-phosphatase receptor type H (PTPRH, SAP-1) is a 912-residue transmembrane phosphatase whose extracellular segment carries five fibronectin-type III repeats and a single catalytic domain that dephosphorylates Src-family kinases. A single transmembrane helix anchors the protein to the apical brush border of intestinal epithelium, while a short cytoplasmic tail binds ezrin-radixin-moesin proteins. Constitutively expressed in small intestine and colon, PTPRH localizes to microvilli and tight-junction plaques. Antibodies raised against the ectodomain or catalytic peptide detect native, glycosylated and proteolytically shed forms with negligible cross-reactivity to other receptor PTPs, enabling selective immunoblot and immunohistochemical visualization in mouse intestinal homogenates and sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.