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Rabbit Anti-Mouse Protein Kinase D2 (PKD2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse protein kinase D2. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse protein kinase D2.
Specifications
Target Information
Mouse protein kinase D2 (PKD2, PRKD2) is an 878-residue serine/threonine kinase possessing an N-terminal tandem C1A-C1B diacylglycerol-binding module, a central pleckstrin-homology domain for membrane docking, and a C-terminal catalytic core that autophosphorylates Ser707 and Ser711 upon activation. Expressed in spleen, thymus and brain, PKD2 cycles between cytosol and trans-Golgi network, binding phosphatidic acid and diacylglycerol-rich membranes. Antibodies raised against the catalytic domain or phospho-Ser707 detect native, active and cleaved forms with negligible cross-reactivity to PKD1 or PKD3, enabling selective immunoblot and immunofluorescence analysis in mouse tissue homogenates and cultured cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.