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Rabbit Anti-Mouse Protein Kinase D1 (PKD1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse protein kinase D1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse protein kinase D1.
Specifications
Target Information
Mouse protein kinase D1 (PKD1, PRKD1) is an 875-residue serine/threonine kinase comprising a diacylglycerol-binding C1A-C1B tandem at the N-terminus, a central PH domain for membrane docking, and a C-terminal catalytic core that autophosphorylates Ser744/Ser748 upon activation. Constitutively expressed in brain, heart and salivary glands, PKD1 cycles between cytosol and trans-Golgi network, binding to phosphatidic acid and diacylglycerol-rich membranes. Antibodies raised against the catalytic domain or phospho-Ser744/748 detect native, active and cleaved forms with negligible cross-reactivity to PKD2 or PKD3, enabling selective immunoblot and immunofluorescence analysis in mouse tissue homogenates and cultured cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.