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Rabbit Anti-Mouse Protein Kinase B Alpha (PKBa) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse protein kinase B alpha. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse protein kinase B alpha.
Specifications
Target Information
Mouse protein kinase B alpha (Akt1) is a 57-kDa serine/threonine kinase ubiquitously expressed in murine tissues, central to PI3K-Akt signaling. Activated by growth factors, cytokines, and metabolic cues via phosphorylation, it regulates downstream targets controlling cell survival, proliferation, glucose metabolism, and cytoskeletal remodeling. Critical for mouse embryonic development, tissue homeostasis, and stress responses, it modulates physiological processes from muscle growth to immune function. Dysregulated activation associates with cancer, diabetes, and neurodegenerative disorders in murine models. As a key mediator of pro-survival and metabolic signaling networks, mouse Akt1 is a critical target for studying disease pathogenesis and developing kinase-targeted therapeutics.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.